Why Can Only Some Animals Regenerate? Killifish Study is Revealing | @Planaria1

Why Can Only Some Animals Regenerate? Killifish Study is Revealing  | @Planaria1

MBL Fellow Alejandro Sánchez Alvarado of the Stowers Institute has published an exciting paper in Science describing genetic mechanisms that can explain why some vertebrates can regenerate body parts while others — such as humans — cannot. In the Twitter thread below, Sánchez Alvarado explains the genesis of the research discovery, including how he first met first author Wei Wang in the MBL Embryology course, which Sánchez Alvarado formerly co-directed. Wang was working with the fruit fly, Drosophila at the time, but the next year he joined Sánchez Alvarado’s lab at the Stowers Institute and “somehow I managed to convince him to venture with me in trying to develop the killifish to study regeneration,” Sánchez Alvarado writes. Voilà: An important result in a novel research organism! (Click on the Tweet to see the illustrated story in the comments.)

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